What is prurigo nodularis?

Prurigo nodularis (PN) is a skin disease that results in hard, itchy lumps, also known as nodules. The itchiness of the lumps can be extremely uncomfortable, causing people to scratch themselves for relief, which results in bleeding, pain, or more lesions to appear. The itchiness from PN may be worsened by hot weather, sweat, or irritation from uncomfortable clothing material.


Diagnosis and Symptoms of PN


The main symptom of PN is the formation of hard, itchy lumps ranging from very small to about half an inch in diameter. These nodules usually appear on the outer arms, shoulders, legs, and neck and can be debilitating: scratching makes the itching worse and can cause more bumps to appear and/or worsen the existing bumps. In some cases, a skin biopsy will confirm a PN diagnosis.



Kiniksa Prurigo Nodularis Educational Webinar
Prurigo Nodularis Educational Webinar

Learn about Prurigo Nodularis and an investigational therapy being evaluated to treat the condition.

Kiniksa Prurigo Nodularis Clinical Trial Overview
Prurigo Nodularis Clinical Trial Overview

Learn about Kiniksa’s clinical trial for an investigational therapy to treat Prurigo Nodularis.

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Prurigo Nodularis Study

See if you qualify to participate in a clinical trial for Prurigo Nodularis.  

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Prurigo Nodularis Clinical Trials
Clinical Trials 

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PN Resources 


The groups listed below are some of the organizations that can help connect people suffering from prurigo nodularis, and their families, to support and educate. While Kiniksa may provide funding to one or more of these institutions, Kiniksa neither endorses nor is responsible for the content of any of the listed websites or the services provided by these organizations. This is not a complete list of available websites.

National Organization of Rare Diseases (NORD)

National Center for Biotechnology Information (NCBI) 

National Institutes of Health (NIH) 


References: https://rarediseases.info.nih.gov/diseases/7480/prurigo-nodularis

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